ASXL1

Gene

ASXL transcriptional regulator 1

HGNCHGNC:18318 EnsemblENSG00000171456 NCBI Gene171023

Locus: gene with protein productLocation: 20q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA0978

View full nomenclature history (3)

Alias symbolsKIAA0978

Previous namesadditional sex combs like 1, transcriptional regulator, additional sex combs like 1 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Myelodysplastic syndrome

Leukemia, Myeloid, Acute

Neoplasms

Leukemia, Myeloid

Hematologic Neoplasms

Lymphoid neoplasm

Genetic Diseases, Inborn

Tobacco Use Disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.