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ATP1B1

Gene

ATPase Na+/K+ transporting subunit beta 1

HGNCHGNC:804EnsemblENSG00000143153NCBI Gene481
Locus: gene with protein productLocation: 1q24.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Sodium/potassium-transporting ATPase subunit beta-1P05026

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

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Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asATP1B
View full nomenclature history (5)
Previous symbolsATP1B
Previous namesATPase, Na+/K+ transporting, beta 1 polypeptide
Alias namessodium/potassium-transporting ATPase subunit beta-1, sodium pump subunit beta-1, sodium-potassium ATPase subunit beta 1 (non-catalytic)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cardiovascular Diseases
Atrial Fibrillation
Heart Failure
Thrombophilia
Coronary Artery Disease
Fuchs' Endothelial Dystrophy
Corneal Dystrophies, Hereditary

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ATPase Na+/K+ transporting subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-17.
Open TargetsGene–disease associations from the Open Targets Platform.