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ATP2B1

Gene

ATPase plasma membrane Ca2+ transporting 1

HGNCHGNC:814EnsemblENSG00000070961NCBI Gene490
Locus: gene with protein productLocation: 12q21.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPMCA1
View full nomenclature history (3)
Alias symbolsPMCA1
Previous namesATPase, Ca++ transporting, plasma membrane 1
Alias namesplasma membrane calcium-transporting ATPase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodevelopmental Disorders
Genetic Diseases, Inborn
Hypertension
Coronary Artery Disease
Myocardial Infarction
Essential Hypertension
Alcohol drinking
Prostate carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ATPases Ca2+ transporting

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-10-11.
Open TargetsGene–disease associations from the Open Targets Platform.