AURKB

Gene

aurora kinase B

HGNCHGNC:11390 EnsemblENSG00000178999 NCBI Gene9212

Locus: gene with protein productLocation: 17p13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSTK12 · Aik2 · IPL1 · AurB · AIM-1 · ARK2 · STK5 · PPP1R48

View full nomenclature history (13)

Previous symbolsSTK12

Alias symbolsAik2, IPL1, AurB, AIM-1, ARK2, STK5, PPP1R48

Previous namesserine/threonine kinase 12

Alias namesaurora-B, aurora-1, protein phosphatase 1, regulatory subunit 48, aurora- and Ipl1-like midbody-associated protein 1 homolog (rat)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Alzheimer's Disease

Parkinson's Disease

Lysosomal Storage Diseases

Multiple Sclerosis

Autoimmune disorder of central nervous system

Small Cell Lung Carcinoma

Ovarian Neoplasms

Ovarian carcinoma

Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunitsChromosomal passenger complexAurora kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.