BTRC

Gene

beta-transducin repeat containing E3 ubiquitin protein ligase

HGNCHGNC:1144 EnsemblENSG00000166167 NCBI Gene8945

Locus: gene with protein productLocation: 10q24.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asbTrCP · betaTrCP · FBXW1A · Fwd1 · beta-TrCP1 · bTrCP1

View full nomenclature history (7)

Alias symbolsbTrCP, betaTrCP, FBXW1A, Fwd1, beta-TrCP1, bTrCP1

Previous namesbeta-transducin repeat containing

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Substance-Related Disorders

Tobacco Use Disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingF-box and WD repeat domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.