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CBY1

Gene

chibby 1, beta catenin antagonist

HGNCHGNC:1307EnsemblENSG00000100211NCBI Gene25776
Locus: gene with protein productLocation: 22q13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPGEA1 · C22orf2 · PIGEA14 · PIGEA-14 · Chibby · Cby · Chibby1
View full nomenclature history (12)
Previous symbolsPGEA1, C22orf2
Alias symbolsPIGEA14, PIGEA-14, Chibby, Cby, Chibby1
Previous namesPKD2 interactor, golgi and endoplasmic reticulum associated 1, chromosome 22 open reading frame 2, chibby homolog 1 (Drosophila), chibby family member 1, beta catenin antagonist
Alias nameschibby CTNNB1-mediated transcription inhibitor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cerebellar Ataxia
Genetic Diseases, Inborn
Hypothyroidism
Familial prostate cancer
Prostatic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-14.
Open TargetsGene–disease associations from the Open Targets Platform.