Cerebellar Ataxia
Recent clinical, regulatory, research and industry developments relating to this disease.
Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 2 clinical trials expected to report results, the earliest in Q2 2027.
- Q2 2027A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 Gene
- Q2 2028The Benefits of Long-read High-throughput Genomic Sequencing for the Causal Diagnosis of Cerebellar Ataxias
Clinical MilestonesViewHide
- 2026-01-21The Benefits of Long-read High-throughput Genomic Sequencing for the Causal Diagnosis of Cerebellar AtaxiasResults expected Q2 2028
- 2025-12-10A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 GeneResults expected Q2 2027
- 2027-10-01ClinicalUse of a New Smartphone Application, iBlink, to Determine Changes in Eyeblink Conditioning From Home Training in Individuals With Spinocerebellar AtaxiasWithdrawn
- 2026-01-21ClinicalThe Benefits of Long-read High-throughput Genomic Sequencing for the Causal Diagnosis of Cerebellar AtaxiasResults expected Q2 2028
- 2025-12-10ClinicalA Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 GeneResults expected Q2 2027
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Cerebellar Ataxia1
- Nervous System Diseases1
- Stiff-Person Syndrome1
Leading journals1
- Neurology(R) neuroimmunology & neuroinflammation1
Leading researchers8
- Bittner S1
- Doppler K1
- Eisenhut K1
- Engels D1
- Faber J1
- Falk KK1
- Finke C1
- Geis C1
Affiliations (unnormalised)1
- From the Institute of Clinical Neuroimmunology (K.E.)1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.