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SYNE1

Gene

spectrin repeat containing nuclear envelope protein 1

HGNCHGNC:17089EnsemblENSG00000131018NCBI Gene23345
Locus: gene with protein productLocation: 6q25.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC6orf98 · SYNE-1B · KIAA0796 · 8B · Nesprin-1 · enaptin · MYNE1 · CPG2 · dJ45H2.2 · SCAR8 · ARCA1 · Nesp1
View full nomenclature history (16)
Previous symbolsC6orf98
Alias symbolsSYNE-1B, KIAA0796, 8B, Nesprin-1, enaptin, MYNE1, CPG2, dJ45H2.2, SCAR8, ARCA1, Nesp1
Previous nameschromosome 6 open reading frame 98, spectrin repeat containing, nuclear envelope 1
Alias namesmyocyte nuclear envelope protein 1, nuclear envelope spectrin repeat-1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Cerebellar Ataxia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Spectrin repeat containing nuclear envelope familyKASH domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.