CCDC6

Gene

coiled-coil domain containing 6

HGNCHGNC:18782 EnsemblENSG00000108091 NCBI Gene8030

Locus: gene with protein productLocation: 10q21.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Coiled-coil domain-containing protein 6Q16204

Protein · therapeutic target

Clinically validated target · 2 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTST1 · D10S170 · PTC · TPC · H4 · PTC1

View full nomenclature history (10)

Previous symbolsTST1, D10S170

Alias symbolsPTC, TPC, H4, PTC1

Previous namesDNA segment on chromosome 10 (unique) 170, transforming sequence, thyroid-1

Alias namesDNA segment, single copy, probe pH4 (transforming sequence, thyroid-1, thyroid papillary carcinoma

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Non-Small-Cell Lung

Medullary thyroid gland carcinoma

Neurodegenerative Diseases

Neoplasms

Thyroid Neoplasms

Thyroid tumor

Thyroid gland papillary carcinoma

Thyroid Carcinoma, Anaplastic

Adenocarcinoma, Follicular

Adenocarcinoma of Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.