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CCR5

Gene

C-C motif chemokine receptor 5

HGNCHGNC:1606EnsemblENSG00000160791NCBI Gene1234
Locus: gene with protein productLocation: 3p21.31

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

C-C chemokine receptor type 5P51681

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCMKBR5 · CKR-5 · CC-CKR-5 · CKR5 · CD195 · IDDM22
View full nomenclature history (9)
Previous symbolsCMKBR5
Alias symbolsCKR-5, CC-CKR-5, CKR5, CD195, IDDM22
Previous nameschemokine (C-C motif) receptor 5, chemokine (C-C motif) receptor 5 (gene/pseudogene), C-C motif chemokine receptor 5 (gene/pseudogene)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
COVID-19
Virus Diseases
Diabetes Mellitus, Type 1
Acquired Immunodeficiency Syndrome
Pulmonary Disease, Chronic Obstructive
Pneumonia
Colitis, Ulcerative

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesC-C motif chemokine receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.