CD47

Gene

CD47 molecule

HGNCHGNC:1682 EnsemblENSG00000196776 NCBI Gene961

Locus: gene with protein productLocation: 3q13.12

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Leukocyte surface antigen CD47Q08722

Protein · therapeutic target

Clinical-stage target · 2 candidates in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMER6 · IAP · OA3

View full nomenclature history (10)

Previous symbolsMER6

Alias symbolsIAP, OA3

Previous namesCD47 antigen (Rh-related antigen, integrin-associated signal transducer)

Alias namesantigen identified by monoclonal antibody 1D8, antigenic surface determinant protein OA3, integrin associated protein, Rh-related antigen, CD47 glycoprotein, leukocyte surface antigen CD47

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Myelodysplastic syndrome

Smoking initiation

Lupus Erythematosus, Systemic

Hypothyroidism

Atrial Fibrillation

Bipolar Disorder

Leukemia, Myeloid, Acute

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesImmunoglobulin like domain containingIg-like cell adhesion molecule family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.