CD59

Gene

CD59 molecule (CD59 blood group)

HGNCHGNC:1689 EnsemblENSG00000085063 NCBI Gene966

Locus: gene with protein productLocation: 11p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMIC11 · MIN1 · MSK21 · MIN2 · MIN3 · MIRL · MACIF · HRF20 · 16.3A5 · EJ16 · EL32 · G344 · p18-20 · EJ30

View full nomenclature history (21)

Previous symbolsMIC11, MIN1, MSK21, MIN2, MIN3, MIRL, MACIF, HRF20

Alias symbols16.3A5, EJ16, EL32, G344, p18-20, EJ30

Previous namesCD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 antigen, complement regulatory protein, CD59 molecule, complement regulatory protein, CD59 molecule

Alias namesCD59 glycoprotein, membrane attack complex inhibition factor, membrane inhibitor of reactive lysis

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dyskeratosis congenita

Genetic Diseases, Inborn

Neoplasms

Neuromyelitis Optica

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Blood group antigensCD moleculesLY6/PLAUR domain containingComplement system regulators and receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.