CD70

Gene

CD70 molecule

HGNCHGNC:11937 EnsemblENSG00000125726 NCBI Gene970

Locus: gene with protein productLocation: 19p13.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

CD70 antigenP32970

Protein · therapeutic target

Clinical-stage target · 4 candidates in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD27LG · TNFSF7 · CD27L · CD27-L

View full nomenclature history (7)

Previous symbolsCD27LG, TNFSF7

Alias symbolsCD27L, CD27-L

Previous namestumor necrosis factor (ligand) superfamily, member 7

Alias namesCD70 antigen, CD27 ligand

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Severe Combined Immunodeficiency

Lymphoma, Non-Hodgkin's

Neurodegenerative Diseases

Genetic Diseases, Inborn

Neoplasms

Leukemia, Myeloid, Acute

Carcinoma, Renal Cell

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTumor necrosis factor superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.