Back to discover

CDC45

Gene

cell division cycle 45

HGNCHGNC:1739EnsemblENSG00000093009NCBI Gene8318
Locus: gene with protein productLocation: 22q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCDC45L2 · CDC45L
View full nomenclature history (6)
Previous symbolsCDC45L2, CDC45L
Previous namesCDC45 (cell division cycle 45, S.cerevisiae, homolog)-like, CDC45 cell division cycle 45-like (S. cerevisiae), cell division cycle 45 homolog (S. cerevisiae)
Alias nameshuman CDC45

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Microcephaly
Carcinoma, Hepatocellular
Androgen insensitivity syndrome
Neoplasms
Leukemia, Myeloid, Acute
Colorectal Neoplasms
Stomach Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CMG helicase complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.