CDK12

Gene

cyclin dependent kinase 12

HGNCHGNC:24224 EnsemblENSG00000167258 NCBI Gene51755

Locus: gene with protein productLocation: 17q12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCRKRS · CRK7 · CRKR · KIAA0904

View full nomenclature history (6)

Previous symbolsCRKRS

Alias symbolsCRK7, CRKR, KIAA0904

Previous namesCdc2-related kinase, arginine/serine-rich

Alias namesCDC2 related protein kinase 7

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Prostate adenocarcinoma

Neurodegenerative Diseases

Alzheimer's Disease

Lysosomal Storage Diseases

Multiple Sclerosis

Parkinson's Disease

Prostate carcinoma

Urinary bladder carcinoma

Colonic Neoplasms

Carcinoma of liver and intrahepatic biliary tract

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cyclin dependent kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.