CDKN2B

Gene

cyclin dependent kinase inhibitor 2B

HGNCHGNC:1788 EnsemblENSG00000147883 NCBI Gene1030

Locus: gene with protein productLocation: 9p21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asP15 · MTS2 · INK4B · TP15 · CDK4I · p15INK4b

View full nomenclature history (7)

Alias symbolsP15, MTS2, INK4B, TP15, CDK4I, p15INK4b

Previous namescyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Alzheimer's Disease

Glaucoma, Open-Angle

Diabetes Mellitus, Type 2

Glaucoma

Coronary Artery Disease

Glioma

Parkinson's Disease

Basal cell carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cyclin dependent kinase inhibitor 2 family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.