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CENPE

Gene

centromere protein E

HGNCHGNC:1856EnsemblENSG00000138778NCBI Gene1062
Locus: gene with protein productLocation: 4q24

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIF10 · PPP1R61
View full nomenclature history (5)
Alias symbolsKIF10, PPP1R61
Previous namescentromere protein E (312kD), centromere protein E, 312kDa
Alias namesprotein phosphatase 1, regulatory subunit 61

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Seckel syndrome
Microcephalic primordial dwarfism
Autosomal recessive primary microcephaly
Testicular Diseases
Ovarian dysfunction
Diabetic Neuropathies
Thyroid gland carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

KinesinsProtein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.