Disease

Ovarian dysfunction

Clinical development underway

Also known as ovarian failure, ovarian hypofunction, ovarian insufficiency.

Clinical trials

Associated genes

Related proteins

Current focus

Mucin-16 biologyMucin-4 biologyTherapeutic development

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme

All trials

Active

Late-stage

Completed

Recently completed

Cumulative Pregnancy Rate With Lower and Higher Dose of Gonadotropin During Controlled Ovarian Hyperstimulation During IVF Among Expected Poor Responders: a Prospective, Randomized Controlled Trial

N/A · Completed · Peter Kovacs MD

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

PROX10.42 NYAP20.41 SEMA3C0.39 GPC50.38 CTIF0.38 CSMD30.38 MEF2A0.37 NTM0.37 CSMD10.36 ADAMTS30.36 SNTB10.35 GALNTL60.35

Disease biology

6 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Zinc finger E-box-binding homeobox 1via ZEB10.32 Mucin-16via MUC160.29 Mucin-4via MUC40.29 Glucagon-like peptide 2 receptorvia GLP2R0.29 Myosin-7Bvia MYH7B0.28 Serine/threonine-protein kinase ULK1via ULK10.27

Reference

Authoritative identity, definition & identifiers.

Synonyms

ovarian failure, ovarian hypofunction, ovarian insufficiency

References & data sources

Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
Related entities are derived from literature co-mention (studied together) — associative, not causal.