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SEMA3C

Gene

semaphorin 3C

HGNCHGNC:10725EnsemblENSG00000075223NCBI Gene10512
Locus: gene with protein productLocation: 7q21.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSEMAE · SemE
View full nomenclature history (3)
Previous symbolsSEMAE
Alias symbolsSemE
Previous namessema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation
Neurodegenerative Diseases
Coronary Artery Disease
Glaucoma
Glaucoma, Open-Angle
Ovarian dysfunction
Amino Acid Metabolism, Inborn Errors
Atrial septal defect
Subarachnoid Hemorrhage
Alopecia Areata

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

I-set domain containingSemaphorins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.