CHMP1B

Gene

charged multivesicular body protein 1B

HGNCHGNC:24287 EnsemblENSG00000255112 NCBI Gene57132

Locus: gene with protein productLocation: 18p11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCHMP1.5 · C18orf2 · Vps46B

View full nomenclature history (5)

Alias symbolsCHMP1.5, C18orf2, Vps46B

Previous nameschromatin modifying protein 1B

Alias namesVPS46 homolog B (S. cerevisiae)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Gastrointestinal disease

Infections

Neoplasms

Malaria, Falciparum

Spastic Paraplegia, Hereditary

Parkinson's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Charged multivesicular body proteinsESCRT-III associated factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-08-02.

Open TargetsGene–disease associations from the Open Targets Platform.