CHMP4B

Gene

charged multivesicular body protein 4B

HGNCHGNC:16171 EnsemblENSG00000101421 NCBI Gene128866

Locus: gene with protein productLocation: 20q11.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC20orf178 · dJ553F4.4 · Shax1 · SNF7-2 · VPS32B

View full nomenclature history (7)

Previous symbolsC20orf178

Alias symbolsdJ553F4.4, Shax1, SNF7-2, VPS32B

Previous nameschromosome 20 open reading frame 178, chromatin modifying protein 4B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Posterior polar cataract

Early-onset non-syndromic cataract

Neurodegenerative Diseases

Virus Diseases

HIV Infections

Diabetes Mellitus

Diabetes Mellitus, Type 2

COVID-19

Severe Acute Respiratory Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Charged multivesicular body proteinsESCRT-III

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.