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CIB2

Gene

calcium and integrin binding family member 2

HGNCHGNC:24579EnsemblENSG00000136425NCBI Gene10518
Locus: gene with protein productLocation: 15q25.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDFNB48 · USH1J · KIP2
View full nomenclature history (6)
Previous symbolsDFNB48, USH1J
Alias symbolsKIP2
Previous namesdeafness, autosomal recessive 48, Usher syndrome 1J (autosomal recessive)
Alias nameskinase interacting protein 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hearing loss, autosomal recessive
Deafness
Neurodegenerative Diseases
Non-syndromic genetic deafness
Nonsyndromic genetic hearing loss
Hearing Loss

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

EF-hand domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-11-25.
Open TargetsGene–disease associations from the Open Targets Platform.