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CLCNKA

Gene

chloride voltage-gated channel Ka

HGNCHGNC:2026EnsemblENSG00000186510NCBI Gene1187
Locus: gene with protein productLocation: 1p36.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known ashClC-Ka · ClC-K1 · CLCK1
View full nomenclature history (6)
Alias symbolshClC-Ka, ClC-K1, CLCK1
Previous nameschloride channel Ka, chloride channel, voltage-sensitive Ka
Alias namesChloride channel protein ClC-Ka

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Bartter Syndrome
Neurodegenerative Diseases
Heart Failure
Cardiomyopathies
Heart Failure, Systolic
Deafness
Cardiomyopathy, Hypertrophic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CLC chloride channel and transporter family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-25.
Open TargetsGene–disease associations from the Open Targets Platform.