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CNR1

Gene

cannabinoid receptor 1

HGNCHGNC:2159EnsemblENSG00000118432NCBI Gene1268
Locus: gene with protein productLocation: 6q15

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Cannabinoid receptor 1P21554

Protein · therapeutic target

Clinically validated target · 4 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCNR · CB1K5 · CB-R · CB1 · CANN6 · CB1A
View full nomenclature history (7)
Previous symbolsCNR
Alias symbolsCB1K5, CB-R, CB1, CANN6, CB1A
Previous namescannabinoid receptor 1 (brain)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Obesity disorder
Lennox-Gastaut syndrome
Epilepsy
Epilepsies, Myoclonic
Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cannabinoid receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.