CPSF2

Gene

cleavage and polyadenylation specific factor 2

HGNCHGNC:2325 EnsemblENSG00000165934 NCBI Gene53981

Locus: gene with protein productLocation: 14q32.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA1367 · CPSF100

View full nomenclature history (4)

Alias symbolsKIAA1367, CPSF100

Previous namescleavage and polyadenylation specific factor 2, 100kD subunit, cleavage and polyadenylation specific factor 2, 100kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Androgen insensitivity syndrome

Epilepsy

Placental abruption

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cleavage and polyadenylation specific factor subunitsMBL fold containing DNA/RNA interacting subfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.