CRYBA1

Gene

crystallin beta A1

HGNCHGNC:2394 EnsemblENSG00000108255 NCBI Gene1411

Locus: gene with protein productLocation: 17q11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCRYB1

View full nomenclature history (3)

Previous symbolsCRYB1

Previous namescrystallin, beta A1

Alias nameseye lens structural protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Posterior polar cataract

Early-onset non-syndromic cataract

Genetic Diseases, Inborn

Cataract

Diabetes Mellitus, Type 2

Major depressive disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Beta-gamma crystallins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.