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CRYBB2

Gene

crystallin beta B2

HGNCHGNC:2398EnsemblENSG00000244752NCBI Gene1415
Locus: gene with protein productLocation: 22q11.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCCA2 · CRYB2A · CRYB2
View full nomenclature history (4)
Previous symbolsCCA2, CRYB2A, CRYB2
Previous namescrystallin, beta B2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Total congenital cataract
Cataract

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Beta-gamma crystallins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.