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CTSA

Gene

cathepsin A

HGNCHGNC:9251EnsemblENSG00000064601NCBI Gene5476
Locus: gene with protein productLocation: 20q13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGSL · PPGB
View full nomenclature history (10)
Previous symbolsGSL, PPGB
Previous namesprotective protein for beta-galactosidase (galactosialidosis)
Alias namescarboxypeptidase C, lysosomal protective protein, carboxypeptidase-L, carboxypeptidase Y-like kininase, deamidase, lysosomal carboxypeptidase A, urinary kininase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Colorectal Neoplasms, Hereditary Nonpolyposis
Non-immune hydrops fetalis
Coronary Artery Disease
Prostate carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cathepsins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.