CX3CR1

Gene

C-X3-C motif chemokine receptor 1

HGNCHGNC:2558 EnsemblENSG00000168329 NCBI Gene1524

Locus: gene with protein productLocation: 3p22.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

CX3C chemokine receptor 1P49238

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGPR13 · CMKBRL1 · CMKDR1 · V28 · CCRL1

View full nomenclature history (7)

Previous symbolsGPR13, CMKBRL1

Alias symbolsCMKDR1, V28, CCRL1

Previous nameschemokine (C-X3-C) receptor 1, chemokine (C-X3-C motif) receptor 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypothyroidism

Macular Degeneration

Thyroid Diseases

Thyroiditis, Autoimmune

Alcohol drinking

Neoplasms

Retinitis Pigmentosa

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

C-X-3-C motif chemokine receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.