CXCL2

Gene

C-X-C motif chemokine ligand 2

HGNCHGNC:4603 EnsemblENSG00000081041 NCBI Gene2920

Locus: gene with protein productLocation: 4q13.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

C-X-C motif chemokine 2P19875

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGRO2 · SCYB2 · GROb · MIP-2a · MGSA-b · CINC-2a

View full nomenclature history (8)

Previous symbolsGRO2

Alias symbolsSCYB2, GROb, MIP-2a, MGSA-b, CINC-2a

Previous namesGRO2 oncogene, chemokine (C-X-C motif) ligand 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Placental retention

Neoplasms

Carcinoma, Hepatocellular

Breast Neoplasms

Colorectal Neoplasms

Carcinoma, Non-Small-Cell Lung

Leukemia, Myeloid, Acute

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Chemokine ligands

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.