CYP19A1

Gene

cytochrome P450 family 19 subfamily A member 1

HGNCHGNC:2594 EnsemblENSG00000137869 NCBI Gene1588

Locus: gene with protein productLocation: 15q21.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

AromataseP11511

Protein · therapeutic target

Clinically validated target · 6 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP19 · ARO · P-450AROM · CPV1 · ARO1 · aromatase · CYAR

View full nomenclature history (9)

Previous symbolsCYP19

Alias symbolsARO, P-450AROM, CPV1, ARO1, aromatase, CYAR

Previous namescytochrome P450, family 19, subfamily A, polypeptide 1, cytochrome P450, subfamily XIX (aromatization of androgens)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Aromatase deficiency

Aromatase excess syndrome

Neoplasms

Polycystic Ovary Syndrome

Osteoarthritis

Osteoporosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 19MicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-10.

Open TargetsGene–disease associations from the Open Targets Platform.