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CYP2U1

Gene

cytochrome P450 family 2 subfamily U member 1

HGNCHGNC:20582EnsemblENSG00000155016NCBI Gene113612
Locus: gene with protein productLocation: 4q25

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSPG56 · SPG49
View full nomenclature history (5)
Previous symbolsSPG56
Alias symbolsSPG49
Previous namescytochrome P450, family 2, subfamily U, polypeptide 1, spastic paraplegia 56 (autosomal dominant)
Alias namesspastic paraplegia 49

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Spastic Paraplegia, Hereditary
Genetic Diseases, Inborn
Retinal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 2

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-10.
Open TargetsGene–disease associations from the Open Targets Platform.