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CYP3A4

Gene

cytochrome P450 family 3 subfamily A member 4

HGNCHGNC:2637EnsemblENSG00000160868NCBI Gene1576
Locus: gene with protein productLocation: 7q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP3A3
View full nomenclature history (3)
Previous symbolsCYP3A3
Previous namescytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, cytochrome P450, family 3, subfamily A, polypeptide 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
Hepatitis C
Hepatitis C, Chronic
Infections
COVID-19
Hypocalcemic vitamin D-resistant rickets
Virus Diseases
Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 3

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-10.
Open TargetsGene–disease associations from the Open Targets Platform.