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CYP51A1

Gene

cytochrome P450 family 51 subfamily A member 1

HGNCHGNC:2649EnsemblENSG00000001630NCBI Gene1595
Locus: gene with protein productLocation: 7q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP51 · CP51 · CYPL1 · P450L1 · LDM · P450-14DM
View full nomenclature history (8)
Previous symbolsCYP51
Alias symbolsCP51, CYPL1, P450L1, LDM, P450-14DM
Previous namescytochrome P450, 51 (lanosterol 14-alpha-demethylase), cytochrome P450, family 51, subfamily A, polypeptide 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Early-onset non-syndromic cataract
Cataract
Neurodegenerative Diseases
Heart Arrest
Wolff-Parkinson's-White syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 51

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.