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CYP7B1

Gene

cytochrome P450 family 7 subfamily B member 1

HGNCHGNC:2652EnsemblENSG00000172817NCBI Gene9420
Locus: gene with protein productLocation: 8q12.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSPG5A
View full nomenclature history (4)
Previous symbolsSPG5A
Previous namescytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1, spastic paraplegia 5A (autosomal recessive), cytochrome P450, family 7, subfamily B, polypeptide 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Spastic Paraplegia, Hereditary
Genetic Diseases, Inborn
Major depressive disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 7

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.