Back to discover

DCAF8

Gene

DDB1 and CUL4 associated factor 8

HGNCHGNC:24891EnsemblENSG00000132716NCBI Gene50717
Locus: gene with protein productLocation: 1q23.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asWDR42A · H326 · FLJ35857
View full nomenclature history (4)
Previous symbolsWDR42A
Alias symbolsH326, FLJ35857
Previous namesWD repeat domain 42A

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Lysosomal Storage Diseases
Neurofibromatosis 1
Non-syndromic male infertility due to sperm motility disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingDDB1 and CUL4 associated factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.