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DCDC2

Gene

doublecortin domain containing 2

HGNCHGNC:18141EnsemblENSG00000146038NCBI Gene51473
Locus: gene with protein productLocation: 6p22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDFNB66 · RU2 · KIAA1154 · DCDC2A · NPHP19
View full nomenclature history (7)
Previous symbolsDFNB66
Alias symbolsRU2, KIAA1154, DCDC2A, NPHP19
Previous namesdeafness, autosomal recessive 66
Alias namesnephronophthisis 19

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cholangitis, Sclerosing
Hearing loss, autosomal recessive
Deafness
Ciliopathy
Neurodegenerative Diseases
Nonsyndromic genetic hearing loss

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Doublecortin superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.