DDIT4

Gene

DNA damage inducible transcript 4

HGNCHGNC:24944 EnsemblENSG00000168209 NCBI Gene54541

Locus: gene with protein productLocation: 10q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRTP801 · REDD-1 · REDD1 · Dig2 · FLJ20500

View full nomenclature history (7)

Alias symbolsRTP801, REDD-1, REDD1, Dig2, FLJ20500

Previous namesDNA-damage-inducible transcript 4

Alias namesHIF-1 responsive RTP801

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Leukemia, Myeloid, Acute

Huntington's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.