DMD

Gene

dystrophin

HGNCHGNC:2928 EnsemblENSG00000198947 NCBI Gene1756

Locus: gene with protein productLocation: Xp21.2-p21.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

DystrophinP11532

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMRX85 · BMD · DXS142 · DXS164 · DXS206 · DXS230 · DXS239 · DXS268 · DXS269 · DXS270 · DXS272

View full nomenclature history (14)

Previous symbolsMRX85

Alias symbolsBMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272

Previous namesmental retardation, X-linked 85, dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272

Alias namesmuscular dystrophy, Duchenne and Becker types

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Muscular Dystrophy, Duchenne

dilated cardiomyopathy 3B

Muscular dystrophy

Familial isolated dilated cardiomyopathy

Progressive muscular dystrophy

Neuromuscular disease caused by qualitative or quantitative defects of dystrophin

Cardiomyopathies

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers ZZ-typeMicroRNA protein coding host genesSpectrin repeat containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.