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DNASE1L3

Gene

deoxyribonuclease 1L3

HGNCHGNC:2959EnsemblENSG00000163687NCBI Gene1776
Locus: gene with protein productLocation: 3p14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDNAS1L3 · LSD · D3
View full nomenclature history (8)
Alias symbolsDNAS1L3, LSD, D3
Previous namesdeoxyribonuclease I like 3, deoxyribonuclease 1 like 3
Alias namesDNase gamma, DNaseY, LS-DNase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypothyroidism
Scleroderma, Systemic
Lupus Erythematosus, Systemic
Autoimmune Diseases
Arthritis, Rheumatoid
Thyroiditis, Autoimmune

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-03-11.
Open TargetsGene–disease associations from the Open Targets Platform.