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DYRK1B

Gene

dual specificity tyrosine phosphorylation regulated kinase 1B

HGNCHGNC:3092EnsemblENSG00000105204NCBI Gene9149
Locus: gene with protein productLocation: 19q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMIRK
View full nomenclature history (4)
Alias symbolsMIRK
Previous namesdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Alias namesminibrain-related kinase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Metabolic Syndrome
Neurodegenerative Diseases
Lysosomal Storage Diseases
Alzheimer's Disease
Multiple Sclerosis
Parkinson's Disease
Genetic Diseases, Inborn
Neoplasms
Ovarian carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesDual-specificity tyrosine-regulated kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.