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E2F1

Gene

E2F transcription factor 1

HGNCHGNC:3113EnsemblENSG00000101412NCBI Gene1869
Locus: gene with protein productLocation: 20q11.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRBBP3 · RBP3
View full nomenclature history (3)
Previous symbolsRBBP3
Alias symbolsRBP3
Previous namesretinoblastoma-binding protein 3 (E2F-like)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Benign prostatic hyperplasia
Neurodegenerative Diseases
Alzheimer's Disease
Parkinson's Disease
Multiple Sclerosis
Lysosomal Storage Diseases
Skin Neoplasms
Exocrine pancreatic carcinoma
Familial prostate cancer
Prostatic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

E2F transcription factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.