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EIF3E

Gene

eukaryotic translation initiation factor 3 subunit E

HGNCHGNC:3277EnsemblENSG00000104408NCBI Gene3646
Locus: gene with protein productLocation: 8q23.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asINT6 · EIF3S6 · eIF3-p48
View full nomenclature history (5)
Previous symbolsINT6, EIF3S6
Alias symbolseIF3-p48
Previous nameseukaryotic translation initiation factor 3, subunit 6 48kDa, eukaryotic translation initiation factor 3, subunit E

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dupuytren Contracture
Colonic Neoplasms
Squamous Cell Carcinoma of Head and Neck
Acinar lung adenocarcinoma
Carcinoma of liver and intrahepatic biliary tract
Carcinoma, Ductal, Breast
Exocrine pancreatic carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Eukaryotic translation initiation factor 3

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.