ENTPD6

Gene

ectonucleoside triphosphate diphosphohydrolase 6

HGNCHGNC:3368 EnsemblENSG00000197586 NCBI Gene955

Locus: gene with protein productLocation: 20p11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD39L2 · IL6ST2 · dJ738P15.3 · NTPDase-6

View full nomenclature history (6)

Previous symbolsCD39L2, IL6ST2

Alias symbolsdJ738P15.3, NTPDase-6

Previous namesinterleukin 6 signal transducer-2, ectonucleoside triphosphate diphosphohydrolase 6 (putative)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Smoking initiation

Atrioventricular Block

Non-alcoholic Fatty Liver Disease

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ectonucleoside triphosphate diphosphohydrolase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-15.

Open TargetsGene–disease associations from the Open Targets Platform.