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ERCC8

Gene

ERCC excision repair 8, CSA ubiquitin ligase complex subunit

HGNCHGNC:3439EnsemblENSG00000049167NCBI Gene1161
Locus: gene with protein productLocation: 5q12.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCKN1 · CSA
View full nomenclature history (5)
Previous symbolsCKN1
Alias symbolsCSA
Previous namesCockayne syndrome 1 (classical), excision repair cross-complementing rodent repair deficiency, complementation group 8, excision repair cross-complementation group 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cockayne Syndrome
Genetic Diseases, Inborn
Parkinson's Disease
Intelligence

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WD repeat domain containingERCC excision repair associated

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.