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EYS

Gene

EGF-like photoreceptor maintenance factor

HGNCHGNC:21555EnsemblENSG00000188107NCBI Gene346007
Locus: gene with protein productLocation: 6q12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC6orf180 · EGFL11 · RP25 · EGFL10 · C6orf178 · C6orf179 · dJ1018A4.2 · bA166P24.2 · SPAM · bA307F22.3 · dJ303F19.1 · bA74E24.1
View full nomenclature history (20)
Previous symbolsC6orf180, EGFL11, RP25, EGFL10, C6orf178, C6orf179
Alias symbolsdJ1018A4.2, bA166P24.2, SPAM, bA307F22.3, dJ303F19.1, bA74E24.1
Previous namesEGF-like-domain, multiple 10, eyes shut homolog, chromosome 6 open reading frame 180, EGF-like-domain, multiple 11, retinitis pigmentosa 25 (autosomal recessive), chromosome 6 open reading frame 178, chromosome 6 open reading frame 179, eyes shut homolog (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Retinitis Pigmentosa
Alcohol drinking
Cone-rod dystrophy
Cone rod dystrophy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-09-04.
Open TargetsGene–disease associations from the Open Targets Platform.