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FAT1

Gene

FAT atypical cadherin 1

HGNCHGNC:3595EnsemblENSG00000083857NCBI Gene2195
Locus: gene with protein productLocation: 4q35.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFAT · CDHF7 · CDHR8
View full nomenclature history (6)
Previous symbolsFAT
Alias symbolsCDHF7, CDHR8
Previous namesFAT tumor suppressor (Drosophila) homolog, FAT tumor suppressor homolog 1 (Drosophila)
Alias namescadherin-related family member 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Squamous Cell Carcinoma of Head and Neck
Squamous cell lung carcinoma
Genetic Diseases, Inborn
Nasopharyngeal Neoplasms
Urinary Bladder Neoplasms
Skin squamous cell carcinoma
Nephrotic Syndrome
Carcinoma, Non-Small-Cell Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cadherin related

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.