Back to discover

FBN1

Gene

fibrillin 1

HGNCHGNC:3603EnsemblENSG00000166147NCBI Gene2200
Locus: gene with protein productLocation: 15q21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFBN · MFS1 · WMS · MASS · OCTD · SGS
View full nomenclature history (9)
Previous symbolsFBN, MFS1, WMS
Alias symbolsMASS, OCTD, SGS
Previous namesfibrillin 1 (Marfan syndrome)
Alias namesasprosin, Marfan syndrome

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Aortic Aneurysm

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Fibrillin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.