FGD2

Gene

FYVE, RhoGEF and PH domain containing 2

HGNCHGNC:3664 EnsemblENSG00000146192 NCBI Gene221472

Locus: gene with protein productLocation: 6p21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asZFYVE4

View full nomenclature history (2)

Alias symbolsZFYVE4

Previous namesFGD1 family, member 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial prostate cancer

Prostatic Neoplasms

Arthritis, Psoriatic

Abnormality of serum enzyme levels

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers FYVE-typePleckstrin homology domain containingDbl family Rho GEFs

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.