FGD3

Gene

FYVE, RhoGEF and PH domain containing 3

HGNCHGNC:16027 EnsemblENSG00000127084 NCBI Gene89846

Locus: gene with protein productLocation: 9q22.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFLJ00004 · ZFYVE5

View full nomenclature history (3)

Alias symbolsFLJ00004, ZFYVE5

Previous namesFGD1 family, member 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Anaphylaxis

Parasitic Diseases

Abnormalities, Radiation-Induced

Skin Diseases

Neoplasms

Pancreatic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers FYVE-typePleckstrin homology domain containingDbl family Rho GEFs

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.